Publications

(30) Advances on the merger of electrochemistry and transition metal catalysis for organic synthesis

Christian A. Malapit, Matthew B. Prater, Jaime R. Cabrera-Pardo, Min Li, Tammy D. Pham, Timothy Patrick McFadden, Skylar Blank, and Shelley D. Minteer

Chemical Reviews 2022, 122, 3180.

[review]

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(29) Electrochemical cobalt-catalyzed selective carboxylation of benzyl halides with CO2 enabled by low-coordinate cobalt electrocatalysts

Christian A. Malapit, Mayank Tanwar, Andrew D. Pendergast, Sagar Udyavara,  Wesley D. Beck, Ryan Edison Smith, Selma Kadic, Tommy Primo, Ding B. Wu, Tanner Stone, Henry S. White, Matthew Neurock, Matthew S. Sigman,and Shelley D. Minteer

ChemRxiv, DOI: 10.33774/chemrxiv-2021-thftp

[paper]

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(28) Cobalt-electrocatalytic hydrogen atom transfer for functionalization of unsaturated C–C bonds

Samer Gnaim, Adriano Bauer, Hai-Jun Zhang, Longrui Chen, Cara Gannet, Christian A. Malapit, David Hill, David Vogt, Tianhau Tang, Ryan Daley, Wei Hao, Wesley D. Beck, Hector Abruna, Donna Blackmond, Shelley D. Minteer, Sarah Reisman, Matthew S. Sigman, and Phil S. Baran​

Nature 2022, in press

ChemRxiv 2021 10.33774/chemrxiv-2021-b34zl

[paper]

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(27) One-pot bioelectrocatalytic conversion of chemically inert hydrocarbons to imines

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Hui Chen, Tianhua Tang, Christian A. Malapit, Yoo Seok Lee, Matthew B. Prater, N. Samali Weliwatte, and Shelley D. Minteer

J. Am. Chem. Soc. 2022, DOI: https://doi.org/10.1021/jacs.1c13063

[paper]

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(26) Decarbonylative fluoroalkylation at palladium(II): from fundamental organometallic studies to catalysis

Naish Lalloo, Christian A. Malapit, S. Maryamdokht Taimoory, Conor E. Brigham, and Melanie S. Sanford

​J. Am. Chem. Soc. 2021, 143, 18617

[paper] [supporting information]

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(25) N-Ammonium ylide mediators for selective electrochemical C–H oxidation

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Masato Saito, Yu Kawamata, Michael Meanwell, Rafael Navratil, Debora Chiodi, Ethan Carlson, Pengfei Hu, Longrui Chen, Sagar Udyavara, Cian Kingston, Mayank Tanwar, Sameer Tyagi, Bruce P. McKillican, Moses G. Gichinga, Michael A. Schmidt, Martin D. Eastgate, Massimiliano Lamberto, Chi He, Tianhua Tang, Christian A. Malapit, Matthew S. Sigman, Shelley D. Minteer, Matthew Neurock, and Phil S. Baran

J. Am. Chem. Soc. 2021, 143, 7859

[paper] | [supporting information]

  • Among the most read articles in JACS in May 2021.

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(24) Nickel-catalyzed decarbonylative amination of carboxylic acid esters

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Christian A. Malapit,* Margarida Borrell,* Michael W. Milbauer, Conor E. Brigham, and Melanie S. Sanford (*equal contribution)

J. Am. Chem. Soc. 2020, 142, 5918–5923.

[paper] | [supporting information]

  • Highlighted in Lautens, M.; Larin, E. M. Synfacts 2020, 15, 59. [Link]

  • Highlighted in Green Chemistry Articles of Interest to Pharmaceutical Industry, OPRD 2020, 24, 2369. [Link]

  • Highlighted in Items of Interest to Process R&D Chemists & Engineers, OPRD 2020, 24, 885.

  • Among the most read articles in JACS in March 2020.

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(23) An electrochemical reductive olefin-ketone coupling

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Pengfei Hu, Byron K. Peters, Christian A. Malapit, Julien C. Vantourout, Pan Wang, Jinjun Li, Lucas Mele, Pierre-Georges Echeverria, Shelley D. Minteer, and Phil S. Baran

J. Am. Chem. Soc. 2020, 142, 20979.

[paper] | [supporting information]

  • Highlighted in Davey, S. G. Nature Rev. Chem. 2021, 5, 75. [Link]

  • Among the most read articles in JACS for the year 2021.

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(22) Nickel-catalyzed decarbonylative synthesis of fluoroalkyl thioethers

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Conor E. Brigham, Christian A. Malapit, Naish Lallo, and Melanie S. Sanford

ACS Catalysis 2020, 10, 8315–8320.​

[paper] | [supporting information]

  • Highlighted in Items of Interest to Process R&D Chemists & Engineers, Org. Process. Res. Dev. 2020, 24, 2369. [Link]

  • Among the most read articles in ACS Catalysis in July 2020.

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(21) Biphasic electrocatalytic synthesis of chiral β-hydroxy nitriles

Fangyuan Dong, Hui Chen, Christian A. Malapit, Matthew B. Prater, Min Li, Mengwei Yuan, Koun Lim, and Shelley D. Minteer

 

J. Am. Chem. Soc. 2020, 142, 8374. 

[paper] | [supporting information]

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(20) Selective electroenzymatic oxyfunctionalization by alkane monooxegenase in a biofuel cell

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(19) Mechanism and scope of nickel-catalyzed decarbonylative borylation of carboxylic acid fluorides

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Christian A. Malapit, James R. Bour, Simon R. Laursen, and Melanie S. Sanford

J. Am. Chem. Soc. 2019, 141, 17322–17330.​

[paper] | [supporting information]

  • Featured in Organic Chemistry Portal. [Link]

  • Among the most read articles in JACS for 2019.

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(18) Palladium-Catalyzed Difluoromethylation of Aryl Chlorides and Bromides with TMSCF2H

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Devin M. Ferguson,* Christian A. Malapit,* James R. Bour, and Melanie S. Sanford

*equal contribution

J. Org. Chem. 2019, 84, 3735–3740.

[paper] | [supporting information]

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(17) Base-free nickel-catalysed decarbonylative Suzuki-Miyaura coupling of acid fluorides

  • Highlighted in Lautens, M.; Larin, E. M. Synfacts 2019, 15, 59. [Link]

  • Highlighted in ChemistryViews Magazine.

  • Highlighted in Scientific Update.

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(16) Palladium and nickel-catalyzed decarbonylation to convert thioesters to thioethers

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Naoko Ichiishi, Christian A. Malapit, Łukasz Woźniak, and Melanie S. Sanford

Org. Lett. 2018, 20, 44–47

[paper] | [supporting information]

  • Featured in Organic Chemistry Portal. [Link]

  • Among the most read articles in Organic Letters for 2018.

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(15) Palladium-catalyzed decarbonylative cross-couplings of aroyl chlorides

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  • Among the most read articles in Organic Letters in July 2017.

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(14) Enantioselective arylation of oxindoles using modified BI-DIME ligands

Hari P. R. Mangunuru, Christian A. Malapit, Nizar Haddad, Jonathan T. Reeves, Bo Qu, Sonia Rodriguez, Heewon Lee, Nathan K. Yee, Jinhua J. Song, Carl A. Busacca, and Chris H. Senanayake

Synthesis 2018, 50, 4435–4443

[paper] | [supporting information]

  • Invited paper dedicated to Prof. Scott E. Denmark on the occasion of his 65th birthday. [Link]

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(13) Rhodium-catalyzed addition of aryl boronic acids to 2,2-disubstituted malononitriles

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(12) Palladium-catalyzed acyl C–O bond activation for selective opening of α-methylene-β-lactones with amines

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(11) Rhodium-catalyzed conjugate addition of aryl and alkenyl boronic acids to α-methylene-β-lactones: efficient, stereoselective synthesis of trans-3,4-disubstituted β-lactones

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(10) 1,4-Dicarbofunctionalization of 4-fluoroaryl Grignard and lithium reagents with disubstituted malononitriles

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(9) Development of dieldrin, endosulfan, and hexachlorobenzene-imprinted polymers for array sensing

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(8) Rh-catalyzed transnitrilation of aryl boronic acids with dimethylmalononitrile

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  • Selected as a Hot Paper by Editors.

(7) Transnitrilation from dimethylmalononitrile to aryl Grignard and lithium reagents:

     a practical method for aryl nitrile synthesis

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(6) Nickel- or cobalt-catalyzed cross-coupling of aryl sulfonic acid salts with Grignard reagents

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  • Invited paper published in a special issue dedicated to Prof. Stephen Buchwald on his 60th birthday. [Link]

(5) Recent applications of oxetanes in the synthesis of heterocyclic compounds

Christian A. Malapit, Amy R. Howell

 

J. Org. Chem. 2015, 80, 8489–8495

[Synopsis]

  • Invited JOC Synopsis article.

  • Most read article in JOC in August  2015.

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(4) Pt-catalyzed rearrangement of oxaspirohexanes to 3-methylenetetrahydrofurans: scope and mechanism

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Malapit, C. A.; Chitale, S. M.; Thakur, S. M.; Taboada, R.; Howell, A. R.

J. Org. Chem. 2015, 80, 5196–5209

[paper] | [supporting information]

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(3) A Roadmap for the development of nanotechnology in the Philippines

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Fabian M. Dayrit, Christina C. Binag, Christian A. Malapit

 

A Roadmap for the development of nanotechnology in the Philippines, Chapter 5: Applications of Nanotechnology to the Environment. January 2010.

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(2) Recognition properties of artemisinin-imprinted polymer microspheres

Malapit, C. A.; Lao, K.; Holdsworth, C.; So, R. C.

Kimika 2010, 23, 17–25

[paper] | [journal cover]

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(1) Evaluation of silica sol-gel encapsulation for the controlled release of N,N-diethyl-2-methoxybenzamide

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Chan, A. S.; del Valle, J.; Lao, K.; Malapit, C. A.; Chua, M.; So, R. C.

Phil. J. Science 2009, 138, 13–21.

[paper] | [supporting information]

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